Summary: We have developed the software COPYCAT which provides an easy and fast access to cophylogenetic analyses. It incorporates a wrapper for the program PARAFIT, which conducts a statistical test for the presence of congruence between host and parasite phylogenies. COPYCAT offers various features, such as the creation of customized host-parasite association data and the computation of phylogenetic host/parasite trees based on the NCBI taxonomy.

Availability: COPYCAT and its manual are freely available at http://www-ab.informatik.uni-tuebingen.de/software/copycat.

Contact: auch AT informatik.uni-tuebingen.de

Supplementary information: Results of the real-world example can be found at http://www-ab.informatik.uni-tuebingen.de/software/copycat or Bioinformatics online.